Formulation

Each tablet contains:
Methylprednisolone	4 mg or 16 mg

Methylprednisolone

Metcort®

Prescription Drug

Indication

Endocrine Disorders	Primary or secondary adrenocortical insufficiency (hydrocortisone or cortisone is the first choice; synthetic analogs like dexamethasone may be used in conjunction with mineralocorticoids where applicable; in infancy, mineralocorticoid supplementation is of particular importance) Congenital adrenal hyperplasia Nonsuppurative thyroiditis Hypercalcemia associated with cancer
Rheumatic Disorders	As adjunctive therapy for short-term administration (to tide the patient over an acute episode or exacerbation) in: Post-traumatic osteoarthritis Synovitis of osteoarthritis Rheumatoid arthritis, including juvenile rheumatoid arthritis (selected cases may require low-dose maintenance therapy) Ankylosing spondylitis Acute and subacute bursitis Acute nonspecific tenosynovitis Acute gouty arthritis Psoriatic arthritis Epicondylitis
Collagen Diseases	During an exacerbation or as maintenance therapy in selected cases of: Systemic lupus erythematosus Polymyalgia rheumatica Systemic dermatomyositis (polymyositis) Giant cell arteritis Acute rheumatic carditis
Dermatologic Diseases	Pemphigus vulgaris Severe erythema multiforme (Stevens-Johnson syndrome) Bullous dermatitis herpetiformis Exfoliative dermatitis Mycosis fungoides Severe seborrheic dermatitis Severe psoriasis
Allergic States	Control of severe or incapacitating allergic conditions intractable to adequate trials of conventional treatment: Bronchial asthma Seasonal or perennial allergic rhinitis Allergic contact dermatitis Atopic dermatitis Serum sickness Drug hypersensitivity reactions
Ophthalmic Diseases	Severe acute and chronic allergic and inflammatory processes involving the eye and its adnexa, such as: Herpes zoster ophthalmicus Anterior uveitis (iritis, iridocyclitis) Diffuse posterior uveitis and choroiditis Chorioretinitis Optic neuritis Sympathetic ophthalmia Anterior segment inflammation Allergic conjunctivitis Keratitis Allergic corneal marginal ulcers
Gastrointestinal Diseases	To tide the patient over a critical period of the disease in: Ulcerative colitis Regional enteritis Crohn’s disease
Respiratory Diseases	Symptomatic sarcoidosis Berylliosis Fulminating or disseminated pulmonary tuberculosis when used concurrently with appropriate antituberculous chemotherapy Loeffler’s syndrome not manageable by other means Aspiration pneumonitis
Hematologic Disorders	Idiopathic thrombocytopenic purpura in adults Erythroblastopenia (RBC anemia) Secondary thrombocytopenia in adults Acquired (autoimmune) hemolytic anemia Congenital (erythroid) hypoplastic anemia
Neoplastic Diseases	For palliative management of: Leukemias and lymphomas in adults Acute leukemia in children
Edematous States	To induce diuresis or remission of proteinuria in nephrotic syndrome, without uremia, of the idiopathic type or that due to lupus erythematosus
Nervous System Disorders	Acute exacerbations of multiple sclerosis Management of edema associated with brain tumor
Organ Transplantations
Other Uses	Tuberculous meningitis with subarachnoid block or impending block when used concurrently with appropriate antituberculous chemotherapy Trichinosis with neurologic or myocardial involvement

Dosage and Administration

For more information on safety, precaution and other information about this product, please see the Product Insert.

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