Clindamycin Hydrochloride

Klindex® Capsule

Prescription Drug

Indication

• For the treatment of serious infections caused by susceptible microorganisms:

• Lower respiratory tract infections including bronchitis, pneumonia, empyema, and lung abscess
• Upper respiratory tract infections including tonsillitis, pharyngitis, sinusitis, otitis media, and scarlet fever
• Skin and skin structure infections including inflammatory acne vulgaris, furuncles, cellulitis, impetigo, abscesses, and contaminated wounds. For specific skin and skin structure infections such as erysipelas and paronychia (panaritium), it would seem logical that these conditions would respond very well to clindamycin therapy.
• Gynecological infections including endometritis, pelvic cellulitis, post-surgical vaginal cuff infection, nongonococcal tubo-ovarian abscess, salpingitis and pelvic inflammatory disease when given in conjunction with an antibiotic of appropriate Gram-negative aerobic spectrum.

In cases of cervicitis due to Chlamydia trachomatis, monotherapy with clindamycin has been shown to be effective in eradicating the organism.

• Intra-abdominal infections including peritonitis and abdominal abscess when given in conjunction with an antibiotic of appropriate Gram-negative aerobic spectrum
• Bone and joint infections including acute hematogenous osteomyelitis and septic arthritis
• Septicemia and endocarditis: The effectiveness of clindamycin in the treatment of selected cases of endocariditis has been documented when clindamycin is determined to be bactericidal to the infecting organisms by in vitro testing of appropriate achievable serum concentrations.
• Dental infections such as periodontal abscess and periodontitis
• Pneumocystis jiroveci (carinii) pneumonia in patients with acquired immunodeficiency syndrome (AIDS). In patients who are intolerant to or do not respond to conventional treatment, clindamycin in combination with primaquine has been shown to be efficacious.

• As an alternative treatment of multi-drug resistant Plasmodium falciparum infection when used in combination with quinine or amodiaquine.

Dosage and Administration

For more information on safety, precaution and other information about this product, please see the Product Insert.