Formulation

Doxetaxel 20mg/0.5 mL Concentrate Solution for IV Infusion

Each 0.5 mL concentrate solution for intravenous infusion contains:
Anhydrous Docetaxel	20 mg

Diluent (Solvent) Vial
Ethanol	0.195 mL
Water for Injection q.s.	1.5 mL

Doxetaxel 40mg/mL (80 mg/2 mL) Concentrate Solution for IV Infusion

Each mL concentrate solution for intravenous infusion contains:
Anhydrous Docetaxel	40 mg

Diluent (Solvent) Vial
Ethanol	0.78 mL
Water for Injection q.s.	6 mL

Docetaxel

Docetax®

Prescription Drug

Indications

Breast Cancer

In combination with doxorubicin and cyclophosphamide, for the adjuvant treatment of patients with operable, node-positive breast cancer.
In combination with doxorubicin for the treatment of patients with locally advanced or metastatic breast cancer who have not previously received cytotoxic chemotherapy for this condition.
As monotherapy for the treatment of patients with locally advanced or metastatic breast cancer after failure of cytotoxic chemotherapy. Prior chemotherapy should have included an anthracycline or an alkylating agent.
In combination with trastuzumab, for the treatment of metastatic breast cancer whose tumors overexpress HER2 and without prior chemotherapy for metastatic disease.
In combination with capecitabine, for the treatment of patients with locally advanced or metastatic break cancer after failure of prior anthracycline-containing chemotherapy.

Non-Small Cell Lung Cancer (NSCLC)

As monotherapy for the treatment of patients with locally advanced or metastatic NSCLC after failure of prior chemotherapy.
In combination with cisplatin, for the treatment of patients with unresectable, locally advanced or metastatic NSCLC who have not previously received chemotherapy for this condition.

Ovarian Cancer

For the treatment of metastatic ovarian cancer after failure of first-line or subsequent theraphy

Prostate Cancer

In combination with prednisone or prednisolone, for the treatment of patients with androgen independent (hormone-refractory) metastatic prostate cancer

Gastric Cancer

In combination with cisplatin and 5-fluorouracil (5-FU), for the treatment of patients with metastatic gastric adenocarcinoma, including adenocarcinoma of the gastroesophageal junction, who have not received prior chemotherapy for metastatic disease

Squamous Cell Carcinoma of the Head and Neck (SCCHN)

In combination with cisplatin and 5-FU, for the induction treatment of patients with locally advanced SCCHN.
As monotherapy, for the treatment of patients with recurrent and/or metastatic SCCHN after failure of previous chemotherapy.

Dosage and Administration

For more information on safety, precaution and other information about this product, please see the Product Insert.

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